Design of an 8-Vessel Dissolution Testing system
for a Pharmaceutical Company

Features

  • Analytical Stations: 8 analytical stations arranged in a highly accessible 4+4 layout.
  • Drive Mechanism: Centrally positioned electronic lift drive ensuring absolute vertical stability.
  • Stirrer Mechanism: Configured for baskets and paddles.
  • Speed Range: Variable speed control from 20 to 300 RPM with better than ±1 RPM accuracy.
  • Shaft Design: Interchangeable snap-fit tool shafts for tool-less changeover.
  • Water Bath Temperature Control: Magnetically coupled pump with PWM controlled heater for accurate thermal circulation.
  • Temperature Accuracy: PT100 sensor based monitoring maintaining ±0.1°C throughout the bath.
  • Pre-Heat Feature: Programmable auto-wake system initializes temperature control before testing.
  • Supports seamless connection to automated sampling collector and sampling manifold.
  • Precision Syringe Pumps: Delivers highly reproducible sample volumes within ±1% accuracy.
  • Simultaneous Sampling: Draws aliquots from all vessels at exact pre-programmed intervals.
  • Automated Media Replacement: Automatically refills vessels with fresh pre-heated media to maintain constant volume.

Automation & User Interface Control System

  • Microprocessor-driven platform with 7-inch capacitive touch LCD.
  • Password protection for various user profiles.
  • Store and execute unlimited user-defined test descriptions.
  • Power Protection: Automatic power failure detection and method resumption.
  • Automatic pre-test system readiness and instrument suitability checklist.
  • Automatic logging of test parameters and print support.
Dissolution Testing System
Automation Control Panel